Mezereum - General symptoms

GENERAL

General

The burning in the palate and throat was somewhat relieved after eating, except the persistent sensation as though the parts had been burnt with hot soup, which continued all the afternoon and even next morning.

during the next day there was a sensation of rawness, roughness, and dryness, which continued very troublesome for several days, and was especially annoying, in the morning after waking,.

Prickling on the posterior portion of the palate and at the base of the tongue.

this with a feeling of warmth gradually increased, with dryness of the tongue, that after a time amounted to a real heat and burning.

this sensation involved only the posterior portion of the palate and tongue.

the anterior portion remained normal.

at first the sensation was thought to be the effect of the Alcohol, but the burning became so violent that it seemed as though he must have chewed several pepper-seeds.

during the next hour he frequently endeavored to relieve this heat and burning by small quantities of water.

as long as the water was held in the mouth there was a slight remission of the burning, but after the water was swallowed the burning returned as violent as ever.

after another half hour, he took a cup of white coffee with relish.

after this, the symptoms became worse and more extended, and then the heat and burning involved the tip of the tongue, inside of the lips, cheeks, and gums.

at the same time there was increased transpiration of the skin, especially of the face, without previous heat,.

Great suggillation on the back of the right hand, above the index finger, without cause from pressure or blow.

it is an irregular spot, about an inch in diameter, bright-colored, without any pain.

together with violent itching on this hard by not on the suggillated place, especially on the wrist, so that he was obliged to rub it until it was sore (second morning),.

Eruption on the wrists, which appeared after violent itching, healed after about three weeks.

while scratching there were no distinct pimples.

after scratching there formed several small superficial dark-brown scabs, a line in diameter.

these at last became quite white and scaly, and seemed conical.

the ulcers when healed had a brownish color, as large as the scab, surrounded by a brownish areola,.

Oft-recurring severe itching, compelling to scratch, now here, now there, on almost all parts of the body, and very soon after taking the drug.

especially on the scalp above the forehead, in one or the other eyebrow, also under the eye.

and especially a persistent, oft-recurring itching on the external ear, and in the left concha. The itching often extended over the whole body.

I felt it simultaneously on back, abdomen, and scalp, impelling to scratch, and relieved by scratching. I could perceive no difference in the time of day. At times it was a burning itching, or a tickling, as from insects, on the chin, the shoulder, the clavicle, the right thorax, along the lower ribs, and the back.

also, the thumb and right middle finger. The later the itching began, the greater the inclination to scratch,.

A biting burning gradually extending from the pharynx over the whole mouth and outer margins of the lips.

in the evening there was pain in the pharynx on swallowing, as if swollen or sore, or like a scraping.

afterwards, severe sticking in the pharynx on empty swallowing.

this condition became very violent and general.

swallowing was very painful, especially to the uvula and arches of the palate (first day),.

A peculiar rubbing sound in the praecordial region in the same spot where the pain had been noticed in the previous proving.

the sound was distinctly heard by himself, less noticed while moving about especially in the evening after lying down, and indeed while lying on the left side, and on taking a deep breath.

associated with a sensation as though the chest were too tight, and sufficient air could not be inspired.

this rubbing sound lasted two or three weeks, with an indescribable sensation of heaviness and of an impediment in the region of the heart,.

Griping colic, spasmodically increasing and decreasing at short intervals.

a pressive-sticking pain low down in the lower abdomen, starting from the middle of the abdomen, at times extending into the left side, with hard tension of the abdomen, transiently relieved by the emission of flatus, with weakness of the body, especially of the lower extremities, with frequent paroxysms of aggravation, when it is intolerable,.

Stool rather hard, in the morning, at short intervals, and only after sitting a long time.

immediately after eating, other pasty evacuations at short intervals, and in the evening, repeated desire as in diarrhoea, and urging, that, however, repeatedly disappeared after the emission of flatus, but at last resulted in a small stool, that was first natural and then pasty, during the evacuation of which the urging was very much increased, after which it immediately ceased,.

GENERAL SYMPTOMS.

All the flesh seemed to soften and waste during the proving,

Emaciation and loss of strength, with tensive pains across the thorax, and dry cough day and night,

Activity and desire to work (second day),

Tremulous condition, as after too much wine (first day),

Irregular actions of the tendons,

Stretching (first day),

Indolence,

Indolent, phlegmatic and weary in the extremities; walking is not agreeable to him,

Indolent, not inclined to do any work; like to be completely inactive; is indifferent to everything; is obliged to force himself to take up his business (second day),

Great indolence and weakness after a deep sleep,

Unusual indolence; every word is an effort (second day),

Very lazy; no desire to work; with constant yawning,

Gradually become listless, languid, and drowsy, and exhibited other signs of approaching narcotism; after six hours she was lying on her back, her countenance sunk and ghastly,

Weariness (seventeenth day),

Great weariness (second day),

Great weariness, was obliged to sleep for an hour (fourth day),

Great weariness, with heaviness and dullness of head (ninth day),

Very weary, sick, and irritable (second day),

Very weary and unusually sick (soon),

So weary in the afternoon that she was obliged to lie down and sleep four hours; with agreeable dreams (with constant faceache, which frequently aroused, but never quite awoke her), (fourth day),

Extremely weary in the morning on rising, but not afterwards during the day (fifth day),

Extreme weariness and anxiety (seventh day),

Overpowering weariness, without being able to sleep, in the evening (second day),

Unusual sinking of strength,

Weakness, relieved after a short nap (after second day),

Great weakness, as in faintness (after a few minutes),

Great weakness, with inclination to sleep (third day),

Great weakness while walking,

Weakness, exhaustion,

General exhaustion, with great inclination to sleep, at least to lie outstretched (second day),

Debilitated, low-spirited, and listless, to such an extent that she almost seemed imbecile,

Very much worn out and pale all day, as though he had not slept enough,

Restlessness,

Unusual restlessness (seventh day),

Great restlessness and peevishness, with redness and heat of the face and forehead,

Sensitiveness to cold air,

Sensitiveness to cold water while washing, in the morning; and also in the teeth, while drinking (second morning),

On washing, in the morning, the water seemed too cold (as after taking cold) he was also very averse to cold air, especially sensitive on the head, even noticed once while sitting in the house, as if cold air were blowing on his head (second day),

Great desire for walking in the open air (soon), and soon after dread of the open air,

While walking, he is inclined to go with the upper part of the body bent forward, to hurry and to sing, though everything is performed with difficulty and constraint, .

Inclination to stretch,

Unusual desire for rest, in the afternoon (second day),

Inclined to be indolent (second day),

Falls asleep late, and after a short nap wakes shortly before midnight, with a sensation as of diminished sensibility of all the extremities, even of the penis and abdomen,

Feeling of great lightness of the body,

Uncomfortable feeling in the whole body, with yawning and stretching, pain in the abdomen and eructations,

General uncomfortable feeling; better towards noon (seventh day),

General sick feeling, ; (second day),

General indescribable sick feeling; on going into a close room this amounted almost to nausea, which disappeared on going into the open air (first day),

Very sick and weary (second day),

Pains in the tibiae and other parts of the body, even while walking,

The parts affected feel, on being touched, as if swollen, which is not the case,

Violent boring in the ankles, especially in the left, and the left side of the forehead,

Transient drawing or jerking here and there, after which a constant aching remains,

Drawing pain through the whole left side of the body, with a sensation of falling asleep, especially acute in the hand and foot,

Wandering-drawing pains in the lumbar region and occiput, also in the shoulders, in the flesh of the thighs, and in various parts of the head,

General oppression, without seated pain (third day),

Stitches in various parts of the body, especially in the left chest, in the evening (third day),

Momentary stitches over the whole body (fourth day),

Slight stitches in various parts of the body side, shoulder, arm, fingers; soon disappearing (first day),

Hot jerking stitches in various parts of the body,

Tearing pains in different parts of the body, while sitting,

Crawling and some stitches in various parts of the body (second day),

Incessant shifting of the pains, which, however, are much inclined to return to the original spot,

In general, the wine half of the body seems more affected than the right,

(The effects of wine seem to be increased by Mezereum),

Symptoms not affected by rest or motion,

Wine and coffee do not seem to affect the action of the drug,

Skin symptoms, affections of bones, and neuralgias most important, especially about teeth and face. Bruised, weary feeling in joints, with drawing and stiffness. Pains of various kinds, with chilliness and sensitiveness to cold air. Bone pains. Eruptions after vaccination. Burning, darting sensation in the muscles, subsultus tendinum. Pains shoot upward and seem to draw patient up out of bed. Semi-lateral complaints. Patient is very sensitive to cold air.

Acrid secretions, pus, leucorrhoea, etc

Violent, irritative burning itching, burning smarting, burning boring, etc

with coldness of part affected Neuralgia; after shingles

Ulcers

Effects of suppressed eczema capitis

As of a cool breeze

Sudden pains, then chilly, sore or numb

Emaciation of part

Gouty-rheumatic-syphilitic dyscrasia

One-sided symptoms, whole or partial; numbness of one side of scalp

Head pain [left], into eyes, malar bones, neck, etc, with lachrymation

Painful skull

Pains outward along brows

Eyes seem dry

Ears feel open to cool wind

Deafness

Facial neuralgias

Cracks in angles of mouth

Dry, dark red mouth

Blunt teeth

Toothache into temples; better cool air

Tongue coated along one side only

Sorethroat in winter

Gastric pain, better milk

Contracted, prolapsed rectum

Glistening particles in stool

Stubborn, leucorrhoea

Dry, tickling cough; unto vomiting; worse hot things

Aching, itching in popliteae

Internal burning with external violent itching in small areas or single parts

Intolerable itching; changes place on scratching

Pruritis senilis

Eruptions ooze acrid, gluey moisture, form thick crusts, with pus beneath, or are chalky white

Milk crust

Deep, hard, painful ulcers; acrid pus, drying into crusts; worse touch and warmth

Bones seem enlarged

Periostitis

Chilly; limbs feel cold

Heat of one hand

Daphne mezereum. Chamaelia germanica. Mezereon, Spurge Olive. (Hilly woods over nearly whole of Europe and Russian Asia.) N. O. Thymelaceae. Tincture of fresh bark gathered just before the plant flowers in February and March.

Bones, affections of. Coccygodynia. Constipation. Contraction of tendons. Crusta lactea. Ear, affections of.

swelling of. Ulcers. Vaccination.

An idea of the virulence of this poison may be gathered from a case reported in Allen's Appendix A pale girl, 14, having been advised to use Mezereum leaves to make her fat and rosy, went into the woods and used them freely on her cheeks and surrounding parts.

Burning soon set in, the whole face swelled enormously, especially nose, eyelids, and hairy scalp.

Severe and painful sneezing set in, delirium, dull, unbearable, pressing pains in forehead, a nauseous dryness in throat and constant irritation to dry cough.

The face soon showed the appearance of erysipelas bullosum; nostrils closed, she could only breathe through mouth; febrile pulse, burning urine.

Oil and compresses were applied, and after the second day desquamation occurred in large pieces.

But health did not return.

Poisoning has also been observed from the effects of the berries dryness and burning of throat and stomach; intense thirst; narcotism, coma, convulsions of eyes and upper limbs were observed.

In a child of four, poisoned with the berries, these symptoms occurred Swollen lips; tongue furred and swollen, protruding, swallowing difficult.

The tongue remained quite raw when other symptoms had passed away (H. W., xxii. 466).

Hahnemann records this A robust man took Mezereum bark for some ailment, and continued it after the ailment disappeared.

Soon, unbearable itching set in all over body, could not sleep a moment.

Thirty-six hours after discontinuing it the itching was still increasing, then a few grains of Camphora ^Camphor removed it.

Mezereum is the vegetable analogue of, and is one of the most important antidotes to, Merc Viv ^Mercurius. Merc Viv ^Merc. and Mez. antidote one another.

Mind, skin, eyes, mucous membranes and bones are affected in much the same way by both; they have the same sensitiveness to damp, cold, and warmth, and the same nightly aggravations.

Nash mentions an exception to the agg. by warmth.

In a man whom he cured with Mez. of obstinate facial neuralgia, the pains were brought on or greatly agg. by eating, and the only relief the man could get was by holding the painful side close to a hot stove.

Only radiated heat was of any use, hot cloths, wet or dry, gave no relief whatever.

Mez. affects the long bones more markedly than others, and the least touch is intolerable; but it has, like Merc Viv ^Merc., a strong affinity for the facial bones and teeth.

With Mez. the decay attacks the roots or sides rather than the crowns (which Merc Viv ^Merc. attacks).

The toothache is agg. at night, agg. by touch, even with the tongue, and is amel. by holding the mouth open and drawing in air.

Neuralgia about the eyes; the pains radiate and shoot downward, and if there is in addition a sensation in the eye itself as if a cold wind were blowing in it the indications will be very strong.

Mez. is one of Hahnemann's anti-psorics, and it meets many psoric manifestations.

Carroll Dunham has recorded (Science of Therapeutics, 462) a notable case of deafness, due to suppressed psora.

A Youth, 17, deaf since four, and incapacitated thereby, secludes himself and broods over his trouble.

Membranes thickened. At the age of three he had an eruption of thick, whitish scabs, hard, almost horny, covering the whole scalp.

There were fissures through which exuded on pressure a thick, yellowish pus, often very offensive.

Much itching and disposition to tear off the scabs with the finger-nails, agg. at night.

The treatment (allopathic) was vigorous A tar cap was placed on the head, and when firmly adherent to the scabs was violently tom off, scabs and all, leaving the whole scalp raw.

Mezereum was painted with a saturated solution of Argentum Nitricum ^{Arg. nit}.

The eruption did not reappear, but from that time the child was deaf.

The eruption was the very counterpart of an eruption observed in a proving by Wehle.

Mez. 30, three globules in a powder of sugar of milk, was given on each of these dates.

February 3, March 1, and September 28, 1857, and January 26, 1858. Improvement set in slowly after the first dose, which was only repeated when the effect of each preceding dose seemed to be exhausted. Finally the hearing was for all practical purposes completely restored. The action of Mez. in catarrhal cases is illustrated in another case (Amer. Hom., xxi. 417). Miss M. R., 39, brunette, had chronic catarrh. The left ear had long been deaf, and the right had begun to fail. There were noises in the ears. Drum membranes retracted and scarred. The symptoms were Excessive sensitiveness to the air, even of a fan, and occasionally a sensation as if air went through to the throat. Mucous membrane of naso-pharynx granular and irritable. A dose of Mez. given before each meal entirely relieved the symptoms. The ulcers of Mez. have thick, yellowish, white scabs. Vesicles appear now and then, and itch and burn. Lint dressings stick to them, and when they are torn away bleeding occurs. Burning vesicles on the sides of the fingers.

and ulcers on finger-joints. With eczema there is intolerable itching, agg. in bed and from touch. Vaccinal eczemas are frequently of the Mez. type. Mez. is often of great service in herpes zoster, both during the eruption and for the neuralgia remaining after, especially if the pains are burning. In a lecture on Mez. by T. S. Hoyne (Med. Vis., xiii. 65) are collected many cases illustrating the action of the remedy. Here is a mental case (in a woman) treated by W. E. Payne No rest when alone.

wants company. Ideas vanish while talking.

cannot repeat what has been learned by heart. Looks through the window for hours without being conscious of objects around. Does not know what she is about.

forgets what she is about to utter.

looks ill-humoured, pale, wretched, fallen away. Apprehensiveness at pit of stomach, as when expecting some very unpleasant intelligence. All symptoms relieved in a single night by Mez. 20. (I give the italics as in the original.) Among neuralgic cases are the following ($51$) Man, 28, violent neuralgia, boring pain in left lower jaw-bone, extending to temple and ear. agg. Night, amel. from pressure. Mez. 3 relieved in two hours (S. R. Geiser). (2) H. G., stout, healthy-looking negro, left supra-orbital neuralgia recurring daily at 9 a.m., increasing till noon, declining till 4 p.m., when it entirely departed leaving no soreness behind. Pain = flow of tears. Mez. 1 cured permanently after other remedies had failed Q. W. Vance). (3) Mrs. X. had pain in right eye-tooth, daily increasing. Felt too long. Pains much agg. by pressure on crown and outside root. Mez. 2 cured (Oehme). (4) Toothache in incisor tooth in lady. Tooth feels elongated, loose, excessively sensitive, with sensation as if being raised out of its socket. Upper part of tooth excessively painful. Mez. 200 cured in a few hours (Hempel). (5) The fastenings of a hammock broke, and a lady on it fell, striking the sacrum and coccyx on the stump of a tree. She suffered excruciating pain. Arnica ^Arn. was applied locally. In a few weeks she came home, and the coccyx was still so tender she could not sit.

"Constipation after confinement" has proved a good indication for Mez. "My stools are as hard as stone, and as large as my arm.

I feel as if they would split me open.

They come in sections like mouthfuls, and I become much exhausted and tremble with weakness.

Every stool is immediately preceded by chills, and followed by long stitches up rectum." Mez. 12 produced a natural stool in twelve hours (H. Noah Martin).

Green discharges according to Cooper strongly indicate Mez.

It has cured a case of dry crust on scalp and falling out of hair, accompanied with short sight.

Daphne laureola, the British representative of the genus, has cured scald-head when Mez. failed.

The symptoms in this case were agg. by day, whereas Mez. has agg. at night.

The pains of D. laureola come on in the morning and affect the entire head or whole left side Guaiacum ^Guaiac. pains are also agg. by day and amel. by warmth (Cooper).

Cooper gives me the following cases ($51$) Woman, 48, had rheumatism which came on ten years before in hands from wearing wet gloves, and extended later to arms and knees.

stiffness on walking with loss of muscular power, agg. in hot weather, "pins and needles" in fingers on elevating arms, cannot grasp things, sometimes one hand burns when other is cold, climacteric flushings.

Great relief from Mez. Ø. (2) Girl, 18, getting thin, with headache across forehead, temples, and eyes, a throbbing with sickness of stomach and water-brash, always agg. by movement; bowels very confined; menses never appeared.

Mez. cured; (3) Pimples on ankles and backs of feet, horrid taste and clamminess of mouth in morning, pimples amel. by hard scratching, sluggish bowels.

Mez. cured. H. B. Esmond (H. R., vii. 41) cured with Mez. 3x a youth, 17, who had been afflicted with "salt Rheum ^rheum" as long as he could remember.

It was absent in summer, but every autumn, as soon as cold weather came, face, neck, hands, and forearms would break out and continue sore till warm weather returned.

Another indication for Mez. is hypersensitiveness of the ear to air.

It has cured a case in which there was a feeling as if air went through the ear to the throat.

The rectum and anus are the seat of many characteristic symptoms, stitches, burning itching.

During stool the rectum prolapses and the sphincter closes upon the protruded part.

Mezereum constricting tendency is noticed in the throat and stomach, and also in the tendons.

The leg is shortened with pain in hip.

Tension in muscles of chest.

Pain and stiffness in muscles of neck.

Cramp-like contraction over chest and back; and across front of chest.

Sensations are Head as if drunk; as if everything in the head would press asunder; as if skull would split; as if top of head gone; as if head bruised; as if head was in an ants' nest.

Eyes as if too large; as if drawn back into head.

Ears as if too open; as if air pouring into them; as if tympanum was exposed to cold air; as if air was distending right external meatus.

Teeth feel too long. Hard palate, feels as if made of wood.

Throat as if narrowing.

As if food remained a long time in stomach.

Stools feel as if they would split anus.

Chest feels too tight.

Limbs feel shortened. As if fire darting through muscles.

As if millions of insects were crawling on him.

Sensation of lightness of body.

Bones are very sore and feel distended.

Diseased parts wither.

Mez. is suited to Light-haired persons; phlegmatic temperament; irresolute.

The plant flowers in very early spring, even when snow is on the ground, and it is suited to complaints which come on in the earliest months of the year. agg.

From cold; damp; cold winds; sudden changes of weather; heat; warm food.

Head pains are amel. wrapping up head.

Prosopalgia amel. by heat of stove (not by other heat).

Drawing in air amel. toothache. agg.

From touch or pressure. agg.

From motion. Lying down agg. itching of scalp.

Stooping amel. headache. agg.

Evening and night. agg.

During menses (burning itching inner side of throat).

Affections go from above downward; from within outward; and from right to left.

DAPHNE MEZEREUM, SPURGE OLIVE.

The pathogenesis of Mezereum belongs to the same category as Manganese. It is composed almost entirely of provings published in the (1805) and the fourth volumes of the (1825) -the latter being avowedly made with the mother tincture. The only additions here are the communications from the two students, of whom "H" was Hering. Of these we have no information. (See Cyclop. of Drug Pathogenesy, III, 301.).

In early spring, when the shrub is about to bloom, its bark is gathered. Originally the juice of the fresh green bark was pressed out and preserved, mixed with equal parts of alcohol, and raised to the homoeopathic dynamization by shaking. This juice, when it touches the skin, causes a long continued, very painful burning. But since the medicinal virtue of this bark does not consist in its volatile parts, it will be better to dry it and powder it, and then to triturate it with 100 parts of sugar of milk, and then to potentize it like the other dry medicinal substances, as directed in the first part of this work.

Dr. Stapf, the Medicinal Councilor and baronet, has given in No. 2 of the fourth volume of the a summary view of the chief properties of this very active drug.

Mezereum medicine has so far proved itself useful in diseases which were accompanied by the following symptoms

Humid itching eruption on the head and behind the ears; inflammation of the eyes; chronic leucorrhoea; shortening of a lower limb; nightly itching of the body.

The abbreviations of the names of my fellow observers are as follows ., ; ., ; ., ; ., ; ., ; ., , ., ; ., ; and , two medicinal students in Leipzig.

MEZEREUM.

Not accessible.

In a syphilitic subject taking M. in decoction for nodes.

From four berries swallowed by a man, after mastication.

Not accessible.

(TO HOME) Effects of decoction of bark when given for nodes, etc.

General statement.

From a purgative dose.

From twelve grains of powdered root, in a girl.

(To A. H.) From berries swallowed by a boy after mastication.

From berries; with burning in throat and diarrhoea.

General statement.

Pinching pain in the abdomen, increasing and decreasing spasmodically, recurring with short intermissions, with pressive shooting pain, deep down in the hypogastrium, drawing occasionally from the middle of the abdomen into the left side, with hard distension of the abdomen, transiently relieved by discharge of flatus.

accompanied with lassitude of the body, especially of the lower limbs, frequently recurring with aggravation and then intolerable.;.

From berries in a man.

Pretty hard stool, in the morning, with brief intermissions, after sitting a long time.

immediately after the meal, again with brief intermissions, pappy stools.

in the evening, again an urging, as for diarrhoea, but this repeatedly disappears with a discharge of flatus, until finally a small stool, at first regular, then pappy, follows.

at this evacuation, the tenesmus first increased violently and then was allayed.;.

* * * * *

Pressive, tight pain in the posterior part of the chest, when the body is straightened.

this pain is much aggravated by deep respiration, and it then passes through the whole of the lower part of the chest.

the pain is hardly perceptible when bending forward, but it appears as a sort of rheumatism when, moving his arms, he bends considerably backward.;.

From too long external application as an exutory.

Not found.

Daphne mezereum. E. Stapf. Thymelaceae.

The principal use of Mezereum is in eruptions and ulcerations.

The most violent and important of its symptoms are those of mucous membranes, skin and periosteum. The outer surfaces of the body are in a constant state of irritation.

nervous feelings, biting, tingling, itching, changing place from scratching. Even when there is nothing to be seen, there is violent itching and the patient rubs and scratches until the part becomes raw and then burns.

itching changes place.

the part becomes cold after scratching, cold in spots. Itching changing place after scratching, especially when associated with no visible cause.

As soon as he gets warm in bed or as soon as he goes into a warm room, the itching begins. Formication, itching, biting. The patient is so nervous that he is compelled to move, to change positions.

Vesicular eruptions upon the skin, running a certain course, itching, burning like fire; dries into a crust and disappears; a new crop appears near or in the same place. Vesicles form crusts beneath which is ulceration; these crusts turn white, chalk-like, are thick, tough and leathery.

They are often elevated; fluctuation beneath the crusts; pressure causes thick, white pus, sometimes yellow-white, to ooze forth; violent itching. The pains are aggravated by cold, but the itching and restlessness are worse from beat. A child tears. at the eruption with its fingers when the crusts are present.

Scald-head; thick, white, elevated crusts; copious, white or yellow white pus, often offensive, putrid; vermin are often found among the crusts. Acrid pus eating away the hair; the eruption spreads to any part of the scalp, especially to the top; it is also found beneath the ears, and about the face and chin.

Eruptions with much itching.

skin eruptions followed by ulcers.

discharging a thick, white, offensive matter.

Especially useful where eruptions have been suppressed by Zincum Metallicum ^zinc ointment, mercurial salve, etc. Eruptions on the face, eyes, ears and scalp in child or adult, which have disappeared under the use of some ointment and inveterate catarrhal conditions have resulted, or in which eye symptoms have developed.

conjunctiva chronically swollen, ectropion, granular lids, conjunctival surfaces like raw beef.

fissures in the comers of the eye.

red cicatrices about the eyes where the eruptions have been.

dry spots and enlarged veins about the eyes and nose.

skin feels indurated.

Offensive and troublesome catarrh of the nose.

incrustations, thickening of the mucous membrane, ulceration.

he hawks thick, yellow matter out of the throat.

has been cauterized, atomized, etc., and yet the offensive ozoena remains. The periosteum is affected so that it breaks down. Advanced state of atrophic degeneration of the mucous membranes of the throat and nose.

In the throat, thickening, burning, chronic redness, tumefaction, smarting, soreness on swallowing; granulations and ulcerations of the throat.

Perforating ulcers of the soft palate, all due to suppressed eruptions. Give the remedy and you will have a copious eruption in the original place.

if not, there will be no relief. Often the deafness cannot be cured, because the drum of the ear or the whole ear is destroyed, is white, chalky, and contains no blood-vessels.

a state of atrophic catarrh, so that there is too much structural change for hearing to be restored, yet the patient can be cured.

When outward manifestations are pronounced, its internal manifestations are scanty. It tends to manifest the sufferings of the body on the skin.

it throws the physical evils to the surface, hence, the Mez patient is in fairly good health when the eruptions are out.

when they are suppressed, then catarrhal affections, bone diseases, nervous disorders, strange mental symptoms constipation, rheumatism, and joint symptoms appear.

he becomes a mental wreck.

Religious or financial melancholy; melancholy which shapes itself upon the patient's business; indifference to everybody and everything; irritable; thought is difficult; memory weak; absent minded; has no rest when alone, yet averse to talking. Insanity with melancholy, sadness, and a history of eruptions that have called for Mez

Violent headaches and brain affections; pains rending, tearing; boring; head painful to touch; syphilitic affection of the brain; headaches through the sides of the head as if in the bone; feels as if the head would be crushed (closely related to Merc Viv ^Merc. and Kali Iodatum ^{Kali iod}.).

The hair mats together.

"Head covered with thick, leather-like crusts, under which thick, white pus collects here and there, and glues the hair together.

Scabs on the head look chalky and extended to the eyebrows and nape of neck.

Elevated, white, chalk-like scabs with ichor beneath, breeding vermin."

Neuralgias, sciatica, pain in the spine, in the brachial plexus and down the arms; neuralgia of the face; all following suppressed eruptions.

The Mez patient is sensitive to warm air as far as the skin and. eruptions are concerned, but very sensitive to damp or cold weather as to the neuralgias. After the eruptions have given place to internal manifestations, the patient is chilly, sensitive to the changes of the weather, worse in stormy weather.

worse after a bath, because he takes cold and his internal complaints are aggravated. The eruptions are aggravated after washing.

When the eruptions are not out, the skin is hot and he wants something to cool it; he is better from cool water; there is simply a redness at this time. The itching is aggravated from bathing in warm water.

Ulceration about the roots of the teeth; a scrofulous condition of the gums, which bleed, settle away from the teeth; the teeth decay suddenly.

The face is sickly, full of ulcers, old scars, boils, etc. The anaemic face may flush up at times, but it is usually pale, gray, and waxy, expressive of a cachexia met with in some bone diseases.

Sensation of goneness, fear, apprehension, faintness in the stomach, as if something would happen.

every shock, pain and hearing bad news, cause this apprehensive, hungry, faint, weak, all-gone feeling in the pit of the stomach. It comes on when the door-Belladonna ^bell rings, if the patient is expecting the postman, while waiting at the depot for the arrival of a friend or the departure of the cars.

on being introduced to sonic one, he experiences a thrill beginning in the stomach is "frightened in the stomach.".

Caladium Seguinum ^Cal., Kali Bich ^{Kali bich}., Phosphorus ^Phos. and Mez. have this. These "solar-plexus" individuals often have a deep cracked tongue and are hard to cure.

Inflammatory rheumatism, worse from the warmth of the bed and at night; worse from touch; pains run down the bones; bursting sensation in the bones. They feel enlarged; tearing pains in the periosteum, necrosis, caries, fistulous openings discharging briny particles and large ulcers surrounded by pustules.

Pains in the long bones, especially tibia.

Facial neuralgia or toothache, when the pains are greatly worse by eating or motions of the jaws, better by radiate heat.

Nose; vesicular eruptions, with excoriations, formation of thick scabs, worse at night; zona.

Pains in the long bones, especially the tibia are sometimes greatly relieved by Mezereum. I once cured a very obstinate case of facial neuralgia with it. The pains were brought on, or greatly aggravated, by eating, and the only relief he could get was to hold that side of his face as near as he could to a hot stove. Hot cloths, wet or dry, or any other heat applied did not relieve.

Zona. Skin diseases, etc. See Materia Medica.

Dose

Sixth to thirtieth potency.

Region

SKIN

Nerves or bones Head Face Jaws

Mucous membranes Mouth

Stomach

One side

Characteristics

only lie or stand. Arnica ^Arn. internally and externally for two weeks had no influence. Mez. 2 cured in five days (Oehme).